Cells in population or multicellular organisms possess a phenomenon in which they lose their vigor. Why is this cell vigor-loss mechanism conserved in multicellular organisms? During development, a large amount of programmed cell death occurs, playing a crucial role in processes such as morphogen switching, morphogenetic movements, and the elimination of cells that have failed to differentiate. In adults, cell competition functions as a tumor suppression mechanism by removing precancerous cells. Additionally, maintaining stem cells involves inducing selective cell death to preserve their quality. Organisms have a maximum lifespan beyond which they cannot survive. Although aging has been evolutionarily conserved, our understanding of its biological role is still limited.

In addition to cell death and organismal death, cells, and organisms have developed various responses to cope with environmental changes and stress, which can lead to a decline in vigor. In extreme cases, they reduce their overall metabolism and enter states such as dormancy or hibernation.

The aim of this conference is to discuss how the regulation of cell vigor influences phenotypes at the level of cell populations and organisms, drawing on research in areas such as cell death, control of cell fate, stem cells, cellular stress responses, aging, and hibernation.

Approaches to researching cell vigor span a wide range of fields, including live imaging, genetics, molecular biology, biochemistry, and metabolism. In order to deepen our understanding of the mechanisms underlying the regulation of cell vigor, we look forward to research exchanges across the hierarchy of technologies and research subjects in order to understand the mechanisms of cell vigor.

Invited Speakers:

Ulrich Brinkmann (Roche Innovation Center Munich, Penzberg, Germany) Online presentation

Tatsushi Igaki (Kyoto University, Japan)

Akiko Koto (National Institute of Advanced Industrial Science and Technology, Japan)

Sharad Kumar (University of South Australia, Australia)

Kyoko Miura (Kyushu University, Japan)

Atsushi Miyawaki (RIKEN Center for Brain Science, Japan)

Hozumi Motohashi (Tohoku University, Japan)

Shigekazu Nagata (Osaka University, Japan)

Yasushi Okada (The University of Tokyo, Japan)

Natsuki Shinoda (The University of Tokyo, Japan)

Yusuke Toyama (National University of Singapore, Singapore)

Yuichi Wakamoto (The University of Tokyo, Japan)

Benjamin Weaver (The University of Texas Southwestern Medical Center, USA)

Yoshifumi Yamaguchi (Hokkaido University, Japan)

Shosei Yoshida (National Institute for Basic Biology, Japan)

Junying Yuan (Chinese Academy of Sciences, China)

Tentative Schedule

Day 1: 2025.11.6 (Thr)

12:00 - 13:00   Registration

13:00 - 13:15   Opening Remarks

13:15 - 14:30  Session 1

14:30 - 14:45   Coffee Break and Group Photo

14:45 - 16:15   Session 2

16:15 - 16:30   Coffee Break

16:30 - 18:30   Session 3

18:30 - 20:30   Mixer Dinner    

Day 2: 2025.11.7 (Fri)                                  

9:00 - 11:15    Session 4

11:15 - 11:30   Coffee Break               

11:30 - 13:00   Session 5

13:00 - 14:30   Lunch along with Poster session

14:30 - 15:30   Short talks selected from the posters

15:30 - 15:45   Closing Remarks

15:50              Departure

Invited Speakers and those who wish to attend will be required to register via the following links.

Registration Form ← Click here! (powered by Google Form)

Registration deadline: October 6th, 2025

We encourage participants to consider giving a poster presentation.

Several opportunities for short talks will be offered, based on poster submissions.

※ Privacy Policy and Confidentiality for the 69th NIBB Conference

Abstract submission:

1. Download an abstract template file from here.

2. Email it to the conference office (nibbconf@nibb.ac.jp). 

Abstract submission deadline: September 30th, 2025

Information on meals during the conference:

During the period of the conference, we will serve meals for all participants.

1 mixer dinner on November 6th and 1 lunch on Novermber 7th will be served.

Information of poster presentation:

The poster session is schedule on Novermber 7th along with the lunch.

The short talk session is schedule on the afternoon of the date.

For details, we will announce later.

Organizers:

Masayuki Miura (National Institute for Basic Biology, Japan)

Toshihiko Fujimori (National Institute for Basic Biology, Japan)

Co-Organizer:

Kiyoshi Tatematsu (National Institute for Basic Biology, Japan)

How to access

Accommodation list